Population Genetics

1. In Chihuahuas, being loud and obnoxious is dominant over calm and passive. If 17% of a population of feral Chihuahuas is quiet, what percentage would you expect to be heterozygous for this trait? If your population contained 2,300 dogs, how many homozygous noisy dogs would there be? 2. In frogs, being spotted is dominant ...continues

Population Genetics

3. In plants, flower color is controlled by incomplete dominance, where red and blue are the two homozygous conditions and purple indicates heterozygous. An initial population contains 14 red, 70 purple, and 24 blue individuals. Give exact allele and expected genotype frequencies for this population. Now assume that the heter ...continues

Population Genetics

5. In ladybugs, wings with 4 spots are recessive to those with 2. Assume 11% of the ladybugs have 4 spot wings. If the mutation rate of 2 spot to 4 spot alleles is 0.047, what percentage of the next generation will be heterozygous? 6. You look at two populations of moose, one from Canada, and one from Newfoundland, an islan ...continues

Genotypes and frequencies of phenotypes

In a particular species of guppy, tails can either be long or short and either feathered or straight. A cross between a true-breeding long, feather-tailed male guppy and a true-breeding short, straight-tailed female guppy produces progeny that all have short, straight tails. a) express the genotypes of the adults in the cr ...continues

Unique Haplotypes

a) How many unique haplotypes are present in the collection of 10 sequences (do not include the chimpanzee outgroup sequence)? Label the haplotypes accordingly in the second column of the table (the first two have been labeled for you, by way of example). What is the frequency of the most common haplotype in the sample?

Single Nucleotide Polymorphisms

How many Single Nucleotide Polymorphisms (SNPs) are present among the haplotypes? Which sites are non-segregating (i.e. non-polymorphic)?

Observed frequencies of the SNP3 alleles

What are the observed frequencies of the SNP3 alleles in this sample? Please see the attached file.

Corresponding Genotype Frequencies

Assuming that the haplotypes are drawn from a population in Hardy-Weinberg Equilibrium, what are the corresponding genotype frequencies for SNP3, i.e. the expected frequencies of the GG, GC, and CC SNP3 genotypes? (please show your work)

Hardy-Weinberg Equilibrium

The observed genotype frequencies for SNP7 in this sample are f(AA)= 0.80 , f(AC)= 0.00, and f(CC)=0.20. Is variation at this SNP consistent with the expectations of Hardy-Weinberg equilibrium? Why or why not? (please show your work)

Haplotypes

Using the table below, build a genetic distance matrix which gives the total number of genetic differences between pairs of unique haplotypes in the sample. The first box is filled in for you, by way of an example. Haplotypes 1 2 3 4 5 1 -- 2 2 -- 3 -- 4 -- 5 ...continues