All mutations are not "equal." TACAGACCC is a sequence of DNA which codes for a protein. Please state which mutation will cause the largest change in the protein and why.
Mutation 1 - TACAGACCC is changed to TACAGACTC
Mutation 2 - TACAGACCC is changed to TACAGGCCC
Mutation leads to change in the genetic code. Net effect of mutation is observed in the form of differential coding behavior for protein. In some cases change in codon does not have any effect in the coding output whereas in some cases it causes decisive changes.