3. Mast cells contain granules of histamine which are released upon
exposure to allergens. Depending upon location and amount, this
histamine-release can cause everything from watery eyes to
life-threatening bronchospasm. It was long thought that this might have
an immunologic basis. To probe this possibility, an investigator
generated DNP-specific antibodies of different isotypes. He then
added these antibodies to cultures of mast cells with DNP-coated latex
beads or plain latex beads
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onclusions do you draw these data? Explain your reasoning.
Advance a simple, brief hypothesis about what causes histamine release
from mast cells that is consistent with all the data.
Biology Homework Solutions
#122240
Advance a simple, brief hypothesis about what causes histamine release from mast cells that is consistent with all the data.
Mast cells contain granules of histamine which are released upon exposure to allergens. Depending upon location and amount, this histamine-release can cause everything from watery eyes to life-threatening bronchospasm. It was long thought that this might have an immunologic basis. To probe this possibility, an investigator generated DNP-specific antibodies of different isotypes. He then added these antibodies to cultures of mast cells with DNP-coated latex beads or plain latex beads
(See attached)
What conclusions do you draw these data? Explain your reasoning.
Advance a simple, brief hypothesis about what causes histamine release from mast cells that is consistent with all the data.
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