Chemistry Homework Solutions
Problem
#36319

Determine the primary structure of the peptide

In trying to deduce a primary structure of an peptide sequence...

When does a polypeptide NOT contain a free carboxyl group?  Are all peptides linear (or can they have a cyclic C-terminus)?

What happens when treatment of the intact peptide with 2,4-dinitroflourobenzene (followed by complete hydrolysis and chromatography) yields an amino acid derivitive the involves the amino group of the side chain rather than the alpha-amino  group??  Does this matter to the structure of the primary sequence?

Thank you.

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