Whichforce contributes least to the overall conformation of the protien?
a.Covalent bonds
b. Hydrogen bonds
c. Ionic bonds
d. Hydrophobic interactions
Which amino acid residue when part of a polypeptide can be a hydrogen bond doner to water at pH 7.0?
a.Proline
b. Isoleucine
c. Asparagine
d. Aspartic acid
Alpha Helices are stabilized primarily by:
a. Hydrogen bonds between the main chain peptides bonds
b. Electrostatic interactions between R groups
c. Hydrophobic interactions between alpha-carbons of the main chain
d. Hydrogen bonding between the R groups
The folding of protiens in aqueous solution is driven primarily by:
a. A decrease in the entropy of the peptide upon folding
b. An increase in the entropy of the solvent upon folding
c. A decrease in the enthalpy of the peptide upon folding
d. An increase in the enthalpy of the solvent upon folding
The amino acid residue most likley to be found in a beta turn is:
a. Glycine
b. Alanine
c. Valine
d. Glutamic acid
The characteristic time for atomic vibration in a protien is:
a. milliseconds
b. Microseconds
c. Nanoseconds
d. Picoseconds
Which statement is incorrect about the beta-beta motif?
a. The 2 strands are antiparalle.
b. The region connecting the beta strands usually contains between 1 to 5 amino acids
c. The region connecting the beta-strands is an example of an a beta-tum.
d. The region connecting the beta strands are more likley contains leucine or phenylalaine than glycine or proline
List the following events in the order in which they occure when a protien such as ribonuclease folds into its native structure.
a.formation of alpha-helices
b. formation of beta-strands
c. formation of supersecondary structures or motifs
d. formation of disulfide bonds
The term glycoconjugates is used to describe:
a. Glycolipids
b. Glycoprotiens
c. Carbohydrates
d. Both a and b