The following plasma concentrations (in ug/ml) of a new drug were
recorded in a
patient. Is this data best fit by a single or double compartment model?
Time (hr) conc.
0.26 0.6149
0.51 0.4299
0.77 0.3213
1.02 0.2203
1.25 0.1773
1.51 0.1242
1.76 0.1167
2.02 0.0928
2.25 0.0722
2.51 0.0658
2.76 0.0614
3.02 0.0607
4.02 0.0471
5.01 0.0505
6.01 0.0438
7.01 0.0379
8.01 0.0325
9 0. 0305
10 0 .0282
From my understanding, you just need to either do a single exponential
fit or a more complex exponential fit to see which fits the points
better and determine single vs. double compartment model.
Computer Science Homework Solutions
#105472
The following plasma concentrations (in ug/ml) of a new drug were recorded in a patient.
The following plasma concentrations (in ug/ml) of a new drug were recorded in a patient. Is this data best fit by a single or double compartment model?
Time (hr) conc.
0.26 0.6149
0.51 0.4299
0.77 0.3213
1.02 0.2203
1.25 0.1773
1.51 0.1242
1.76 0.1167
2.02 0.0928
2.25 0.0722
2.51 0.0658
2.76 0.0614
3.02 0.0607
4.02 0.0471
5.01 0.0505
6.01 0.0438
7.01 0.0379
8.01 0.0325
9 0. 0305
10 0 .0282
From my understanding, you just need to either do a single exponential fit or a more complex exponential fit to see which fits the points better and determine single vs. double compartment model.
I think that if a single exponential does not fit, then a "best-fit" model is used, and it can be called a double compartment.
See attached file for full problem description.
The solution provides detailed explanations and answer in the attached files.
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