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Type II immunopathology

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Some Type-II immunopathology mediated autoimmune diseases have manifestations in multiple different organs. Discuss the mechanisms for type II immunopathology, and how antibodies to one single antigen can cause damage in multiple sites throughout the body.

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Solution Summary

This solution explains type II immunopathology, and how it can affect multiple different organs. The solution describes the mechanisms underlying the pathology in these diseases, and gives examples of specific diseases.

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Type II immunopathology is the result of antibodies binding normal body proteins. This results in tissue damaged by mechanisms including complement fixation, or the release of toxic substances from macrophages that bind onto the affected area through ...

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