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Commerce Clause

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Could someone please explain to me how the Commerce Clause affects American business?

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How the Commerce Clause affects American businesses are determined. .

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The Commerce Clause was designed to eliminate an intense rivalry between the groups of those states that had tremendous commercial advantage as a result of their proximity to a major harbor, and those states that were not near a harbor. That disparity was the source of constant economic battles among the states. The exercise by Congress of its regulatory power has increased steadily with the growth and expansion of industry and means of ...

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